The A53T mutation in α-synuclein enhances pro-inflammatory activation in human microglia upon inflammatory stimulus

Krzisch, M., Yuan, B., Chen, W. et al. (8 more authors) (2025) The A53T mutation in α-synuclein enhances pro-inflammatory activation in human microglia upon inflammatory stimulus. Biological Psychiatry, 97 (7). pp. 730-742. ISSN 0006-3223

Abstract

Metadata

Item Type: Article
Authors/Creators:
  • Krzisch, M.
  • Yuan, B.
  • Chen, W.
  • Osaki, T.
  • Fu, D.
  • Garrett-Engele, C.M.
  • Svoboda, D.S.
  • Andrykovich, K.R.
  • Gallagher, M.D.
  • Sur, M.
  • Jaenisch, R.
Copyright, Publisher and Additional Information:

Crown Copyright © 2024. This is an open access article under the terms of the Creative Commons Attribution License (CC-BY-NC-ND 4.0).

Keywords: Disease modeling, Human pluripotent stem cells, Inflammation, Microglia, Parkinson’s disease, Xenotransplantation
Dates:
  • Published: 1 April 2025
  • Published (online): 17 July 2024
  • Accepted: 3 July 2024
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Biomedical Sciences (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 05 Aug 2024 10:37
Last Modified: 27 Mar 2025 10:06
Status: Published
Publisher: Elsevier
Identification Number: 10.1016/j.biopsych.2024.07.011
Related URLs:
Open Archives Initiative ID (OAI ID):

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