Lai, W.-F. orcid.org/0000-0003-0585-6396 and Wong, W.-T. (2021) Nanoparticulate Systems for Bioactive Agent Delivery: What Is the Missing Link in Research for Real Applications? Advanced NanoBiomed Research, 1 (5). 2000099. ISSN 2699-9307
Abstract
Diverse nanoparticulate systems, ranging from polymeric nanoparticles to liposomes, have been exploited as carriers of bioactive agents in recent years; however, the use of these systems has been confined largely to the laboratory context till now. Systems that can successfully be adopted for bioactive agent delivery in practice are few. Herein, such low efficiency in clinical translation is partly due to the lack of awareness of the similar nature between a carrier and a real drug. To rectify this situation, it is important to treat a carrier as an ordinary drug despite its absence of therapeutic effects. The current situation in prevalent bioactive agent delivery research, as well as those routine research practices that should be changed to enhance clinical translation, will be discussed here.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2021 The Authors. Advanced NanoBiomed Research published by Wiley-VCH GmbH. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Environment (Leeds) > School of Food Science and Nutrition (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 31 Jul 2024 12:56 |
Last Modified: | 31 Jul 2024 12:56 |
Published Version: | https://onlinelibrary.wiley.com/doi/10.1002/anbr.2... |
Status: | Published |
Publisher: | Wiley |
Identification Number: | 10.1002/anbr.202000099 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:215490 |