Lai, W.-F. orcid.org/0000-0003-0585-6396, Zhang, D. and Wong, W.-T. (2023) Design of erythrocyte-derived carriers for bioimaging applications. Trends in Biotechnology, 41 (2). pp. 228-241. ISSN 0167-7799
Abstract
Erythrocytes are physiological entities that have been exploited in both preclinical and clinical trials for the delivery of exogenous agents. Over the years, diverse erythrocyte-derived carriers (ECs) have been developed with related patents granted for industrial and commercial purposes. However, most ECs have only been exploited for drug delivery. Serious discussions regarding their applications in imaging are scarce. This article reviews the role of ECs in enhancing imaging efficiency and subsequently delineates strategies for engineering and optimising their preclinical and clinical performance. With a snapshot of the latest developments and use of ECs in imaging, directions to streamline the clinical translation of related technologies can be attained for future research.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Keywords: | erythrocytes; carriers; biodistribution; diagnosis; blood retention; surface functionalisation; imaging |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Environment (Leeds) > School of Food Science and Nutrition (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 25 Jul 2024 16:20 |
Last Modified: | 25 Jul 2024 16:38 |
Status: | Published |
Publisher: | Cell Press |
Identification Number: | 10.1016/j.tibtech.2022.07.010 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:215160 |