Hypoxia‐responsive prodrug of ATR inhibitor, AZD6738, selectively eradicates treatment‐resistant cancer cells

Barnieh, F.M. orcid.org/0000-0001-6110-2746, Morais, G.R., Loadman, P.M. et al. (2 more authors) (2024) Hypoxia‐responsive prodrug of ATR inhibitor, AZD6738, selectively eradicates treatment‐resistant cancer cells. Advanced Science, 11 (34). 2403831. ISSN 2198-3844

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Item Type: Article
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© 2024 The Author(s). Advanced Science published by Wiley-VCH GmbH. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Keywords: ATR; AZD6738; DNA repair; Hypoxia; Prodrugs; Targeted Delivery
Dates:
  • Published: 11 September 2024
  • Published (online): 8 July 2024
  • Submitted: 11 April 2024
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Science (Sheffield) > School of Biosciences (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 16 Jul 2024 13:15
Last Modified: 22 Nov 2024 16:42
Status: Published
Publisher: Wiley
Refereed: Yes
Identification Number: 10.1002/advs.202403831
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