The biased apelin receptor agonist, MM07, reverses Sugen/hypoxia-induced pulmonary arterial hypertension as effectively as the endothelin antagonist macitentan

Williams, T.L., Nyimanu, D., Kuc, R.E. et al. (4 more authors) (2024) The biased apelin receptor agonist, MM07, reverses Sugen/hypoxia-induced pulmonary arterial hypertension as effectively as the endothelin antagonist macitentan. Frontiers in Pharmacology, 15. 1369489. ISSN 1663-9812

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Item Type: Article
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© 2024 Williams, Nyimanu, Kuc, Foster, Glen, Maguire and Davenport. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

Keywords: GPCR, apelin receptor, apelin, MM07, biased signalling, pulmonary hypertension, animal model, cardiovascular
Dates:
  • Published: 9 April 2024
  • Published (online): 9 April 2024
  • Accepted: 26 March 2024
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Chemistry (Leeds) > Organic Chemistry (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 11 Jul 2024 10:15
Last Modified: 11 Jul 2024 10:15
Published Version: https://www.frontiersin.org/journals/pharmacology/...
Status: Published
Publisher: Frontiers
Identification Number: 10.3389/fphar.2024.1369489
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