The green routs for the synthesis of silver nanoparticles (AgNPs) and its multiple applications have attracted many researchers, because silver nanoparticles synthesized by the green method, in addition to being environmentally friendly, are effective in targeting specific tissues and pathogenic microorganisms. The fruit of the Prickly Pear plant has a wide range of secondary metabolites with high regenerative power that can be used for the biosynthesis of AgNPs. Therefore; in this study, green synthesis of nanoparticles was performed using Cactus fruit extract and its antioxidant and antibacterial properties were examined. Antimicrobial activity of extracts and AgNPs against standard strains of gram-positive bacteria such as Staphylococcus aureus (PTCC 16538), Enterococcus faecalis (ATCC 15753), Streptococcus mutans (ATCC 35668), Streptococcus mitis (ATCC 6249), Klebsiella pneumoniae (PTCC 700603), Staphylococcus epidermidis (ATCC 12228) as well as gram-negative Escherichia coli (ATCC 25922) and Pseudomonas aeruginosa (ATCC 27853) were determined by micro-broth dilution method. SEM, UV–Vis, EDAX and XRD techniques confirm successful biosynthesis of silver nanoparticles and average particle size was around 40–65 nm. Silver nanoparticles acted as an inhibitor of DPPH radicals and showed desirable antioxidant properties. MIC and MBC values of experimental pathogens were recorded in the range of 2.34–18.75 µg/mL and 2.34–37.5 µg/mL, respectively. The results showed appropriate antibacterial and antioxidant activity of biosynthesized silver nanoparticles. Therefore, the synthesized silver nanoparticles can be used as natural resources to produce antioxidant and antimicrobial supplements in the pharmaceutical industry.
CORE (COnnecting REpositories)
CORE (COnnecting REpositories)