Swamidatta, Sandesh H. orcid.org/0000-0001-9190-1688 and Lichman, Benjamin R. orcid.org/0000-0002-0033-1120 (2024) Beyond co-expression:pathway discovery for plant pharmaceuticals. CURRENT OPINION IN BIOTECHNOLOGY. 103147. ISSN 0958-1669
Abstract
Plant natural products have been an important source of medicinal molecules since ancient times. To gain access to the whole diversity of these molecules for pharmaceutical applications, it is important to understand their biosynthetic origins. Whilst co-expression is a reliable tool for identifying gene candidates, a variety of complementary methods can aid in screening or refining candidate selection. Here, we review recently employed plant biosynthetic pathway discovery approaches, and highlight future directions in the field.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2024 The Author(s). Published by Elsevier Ltd. Funding Information: We acknowledge funding from UKRI (MR/S01862X/1 and MR/X010260/1). |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Biology (York) The University of York > Faculty of Sciences (York) > Biology (York) > Centre for Novel Agricultural Products (CNAP) (York) |
Depositing User: | Pure (York) |
Date Deposited: | 10 Jun 2024 09:20 |
Last Modified: | 02 Apr 2025 23:27 |
Published Version: | https://doi.org/10.1016/j.copbio.2024.103147 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1016/j.copbio.2024.103147 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:213245 |
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