Pleurotus sajor-caju (Fr.) Singer β-1,3-Glucanoligosaccharide (Ps-GOS) Suppresses RANKL-induced osteoclast differentiation and function in pre-osteoclastic RAW 264.7 cells by inhibiting the RANK/NFκB/cFOS/NFATc1 signalling pathway

Rattajak, P., Aroonkesorn, A., Smythe, C. orcid.org/0000-0001-6526-0565 et al. (2 more authors) (2024) Pleurotus sajor-caju (Fr.) Singer β-1,3-Glucanoligosaccharide (Ps-GOS) Suppresses RANKL-induced osteoclast differentiation and function in pre-osteoclastic RAW 264.7 cells by inhibiting the RANK/NFκB/cFOS/NFATc1 signalling pathway. Molecules, 29 (9). 2113. ISSN 1420-3049

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© 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

Keywords: Pleurotus sajor-caju; glucanoligosaccharide; osteoclastogenesis; osteoporosis; Animals; Mice; Osteoclasts; RAW 264.7 Cells; RANK Ligand; Cell Differentiation; Signal Transduction; NF-kappa B; Pleurotus; Receptor Activator of Nuclear Factor-kappa B; NFATC Transcription Factors; Proto-Oncogene Proteins c-fos; beta-Glucans; Oligosaccharides; Osteogenesis
Dates:
  • Published: 2 May 2024
  • Published (online): 2 May 2024
  • Accepted: 29 April 2024
  • Submitted: 8 March 2024
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Science (Sheffield) > School of Biosciences (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 27 May 2024 10:00
Last Modified: 27 May 2024 10:00
Status: Published
Publisher: MDPI AG
Refereed: Yes
Identification Number: 10.3390/molecules29092113
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