Ali, A., Obireddy, S.R. and Lai, W.-F. orcid.org/0000-0003-0585-6396 (2024) Farnesol as a multifunctional candidate for treatment development. BIOCELL, 48 (2). pp. 163-171. ISSN 0327-9545
Abstract
Farnesol is a C15 isoprenyl alcohol generated from the hydrolysis of farnesyl diphosphate under the action of farnesol synthase in plants. Although this sesquiterpenoid alcohol has been exploited in a wide variety of industrial applications, serious discussions on the possible use of this agent in disease treatment have been scant until now. In this article, we review the current understanding of the physiological properties of farnesol and the potential use of the agent as a candidate for treatment development. In fact, since the turn of the last century, farnesol has been found not only to trigger apoptosis in tumor cells but also to be able to function as a quorum-sensing molecule in Candida albicans to influence infection dynamics. By offering a snapshot of recent advances in research on farnesol, it is expected that this article can provide more insights into future research on farnesol for the development of different treatment strategies.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2024 the Authors. Published by Tech Science Press. This is an open access article under the terms of the Creative Commons Attribution License (CC-BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited. |
Keywords: | Farnesol, Treatment, Natural products, Health effects, Signaling |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Environment (Leeds) > School of Food Science and Nutrition (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 17 May 2024 10:40 |
Last Modified: | 17 May 2024 10:40 |
Status: | Published |
Publisher: | Tech Science Press |
Identification Number: | 10.32604/biocell.2023.043839 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:212568 |
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