The microglial transcriptome of age-associated deep subcortical white matter lesions suggests a neuroprotective response to blood–brain barrier dysfunction

Almansouri, T., Waller, R. orcid.org/0000-0001-5815-8829, Wharton, S.B. orcid.org/0000-0003-2785-333X et al. (5 more authors) (2024) The microglial transcriptome of age-associated deep subcortical white matter lesions suggests a neuroprotective response to blood–brain barrier dysfunction. International Journal of Molecular Sciences, 25 (8). 4445. ISSN 1422-0067

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Item Type: Article
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© 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

Keywords: deep subcortical lesions; microglia; transcriptomic profiling; Humans; Microglia; White Matter; Transcriptome; Blood-Brain Barrier; Male; Female; Aging; Aged; Gene Expression Profiling; Aged, 80 and over; Neuroprotection; Antigens, Differentiation, Myelomonocytic; Antigens, CD
Dates:
  • Published: 2 April 2024
  • Published (online): 18 April 2024
  • Accepted: 16 April 2024
  • Submitted: 22 February 2024
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine and Population Health
Depositing User: Symplectic Sheffield
Date Deposited: 14 May 2024 07:24
Last Modified: 14 May 2024 07:24
Status: Published
Publisher: MDPI AG
Refereed: Yes
Identification Number: 10.3390/ijms25084445
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