Hu, J., Mesnage, R., Tuohy, K. orcid.org/0000-0001-6882-7192 et al. (2 more authors) (2024) (Poly)phenol-related gut metabotypes and human health: an update. Food & Function, 15 (6). pp. 2814-2835. ISSN 2042-6496
Abstract
Dietary (poly)phenols have received great interest due to their potential role in the prevention and management of non-communicable diseases. In recent years, a high inter-individual variability in the biological response to (poly)phenols has been demonstrated, which could be related to the high variability in (poly)phenol gut microbial metabolism existing within individuals. An interplay between (poly)phenols and the gut microbiota exists, with (poly)phenols being metabolised by the gut microbiota and their metabolites modulating gut microbiota diversity and composition. A number of (poly)phenol metabolising phenotypes or metabotypes have been proposed, however, potential metabotypes for most (poly)phenols have not been investigated, and the relationship between metabotypes and human health remains ambiguous. This review presents updated knowledge on the reciprocal interaction between (poly)phenols and the gut microbiome, associated gut metabotypes, and subsequent impact on human health.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | This journal is © The Royal Society of Chemistry 2024. Open Access Article. Published on 19 February 2024. Downloaded on 5/1/2024 10:29:39 AM. This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. |
Keywords: | Humans; Phenols; Phenol; Diet; Gastrointestinal Microbiome |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Environment (Leeds) > School of Food Science and Nutrition (Leeds) > FSN Nutrition and Public Health (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 01 May 2024 09:34 |
Last Modified: | 22 May 2024 13:10 |
Published Version: | http://dx.doi.org/10.1039/d3fo04338j |
Status: | Published |
Publisher: | Royal Society of Chemistry (RSC) |
Identification Number: | 10.1039/d3fo04338j |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:212154 |