The β-Secretase BACE1 Drives Fibroblast Activation in Systemic Sclerosis through the APP/β-Catenin/Notch Signaling Axis

Wasson, C.W., De Lorenzis, E., Clavane, E.M. et al. (14 more authors) (2024) The β-Secretase BACE1 Drives Fibroblast Activation in Systemic Sclerosis through the APP/β-Catenin/Notch Signaling Axis. Journal of Investigative Dermatology, 144 (10). pp. 2197-2210. ISSN 0022-202X

Abstract

Metadata

Item Type: Article
Authors/Creators:
  • Wasson, C.W.
  • De Lorenzis, E.
  • Clavane, E.M.
  • Ross, R.L.
  • Walker, K.A.
  • Caballero-Ruiz, B.
  • Antinozzi, C.
  • Wells, R.
  • Migneco, G.
  • Brown, J.M.Y.
  • Turvey, S.J.
  • Simmons, K.J.
  • Riobo-Del Galdo, N.A.
  • Di Luigi, L.
  • McKimmie, C.S.
  • Del Galdo, F.
  • Meakin, P.J. ORCID logo https://orcid.org/0000-0002-8553-3863
Copyright, Publisher and Additional Information:

© 2024 The Authors. This is an open access article under the terms of the Creative Commons Attribution License (CC-BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited.

Keywords: Fibrosis, Wnt, Notch, Autoimmunity
Dates:
  • Published: October 2024
  • Published (online): 1 April 2024
  • Accepted: 1 March 2024
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM) > Discovery & Translational Science Dept (Leeds)
Funding Information:
Funder
Grant number
BBSRC (Biotechnology & Biological Sciences Research Council)
BB/V014358/1
British Heart Foundation
FS/13/38/33659
Depositing User: Symplectic Publications
Date Deposited: 03 Apr 2024 09:40
Last Modified: 04 Oct 2024 10:20
Status: Published
Publisher: Elsevier
Identification Number: 10.1016/j.jid.2024.03.024
Open Archives Initiative ID (OAI ID):

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