Ben Abdelhadi, A. orcid.org/0009-0004-8945-3790, Rodríguez-Sánchez, S. orcid.org/0000-0003-0678-5411, Ouarsal, R. orcid.org/0009-0004-5568-0012 et al. (7 more authors) (2024) Synthesis, characterization, and magnetic and antibacterial properties of a novel iron(iii) complex (CH3)2NH2[Fe(phen)Cl4]. Materials Advances, 5 (7). pp. 3058-3066. ISSN 2633-5409
Abstract
A novel iron(III) complex (CH3)2NH2[Fe(phen)Cl4] (1) (phen = 1,10-phenanthroline) was synthesized, its structure was fully characterized using different techniques, and its in vitro antibacterial activity against various antibiotic-resistant Gram-positive and Gram-negative bacteria was evaluated. The structure of 1 is made up of mononuclear [Fe(phen)Cl4]− anions and dimethylammonium cations (CH3)2NH2+. Iron(III) is hexacoordinated to two nitrogen atoms of chelating phenanthroline and four chlorides forming a distorted octahedral environment around the metal atom. Complex 1 crystallizes in a triclinic system with the P[1 with combining macron] space group. 3D Hirshfeld surfaces and 2D fingerprint plots show that H⋯Cl interactions are the major contributors in maintaining the total surface. IR and UV-visible spectra indicated the coordination of 1,10-phenanthroline to iron (III) metal. Thermal stability experiments revealed that 1 is stable up to 428 K. Magnetic susceptibility measurements indicated a paramagnetic behavior at high temperatures. In vitro antibacterial activity was explored against two Gram-positive bacteria, Staphylococcus aureus CECT 86 and Listeria monocytogenes CECT 4031, and two Gram-negative bacteria, Escherichia coli CECT 99 and Klebsiella pneumoniae CECT 143T, using the disc diffusion method. Complex 1 clearly showed good activity against these bacteria and is a potential candidate for treating bacterial infections and promoting further development in their treatment.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © The Royal Society of Chemistry 2024. This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence: https://creativecommons.org/licenses/by-nc/3.0/ |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Engineering (Sheffield) > Department of Materials Science and Engineering (Sheffield) |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 08 Mar 2024 10:49 |
Last Modified: | 08 Nov 2024 12:13 |
Status: | Published |
Publisher: | Royal Society of Chemistry (RSC) |
Refereed: | Yes |
Identification Number: | 10.1039/d3ma00971h |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:209874 |