Qi, X., Bertling, K., Torniainen, J. et al. (14 more authors) (Cover date: 1 March 2024) Terahertz in vivo imaging of human skin: Toward detection of abnormal skin pathologies. APL Bioengineering, 8 (1). 016117. ISSN 2473-2877
Abstract
Terahertz (THz) imaging has long held promise for skin cancer detection but has been hampered by the lack of practical technological implementation. In this article, we introduce a technique for discriminating several skin pathologies using a coherent THz confocal system based on a THz quantum cascade laser. High resolution in vivo THz images (with diffraction limited to the order of 100 μm) of several different lesion types were acquired and compared against one another using the amplitude and phase values. Our system successfully separated pathologies using a combination of phase and amplitude information and their respective surface textures. The large scan field (50 × 40 mm) of the system allows macroscopic visualization of several skin lesions in a single frame. Utilizing THz imaging for dermatological assessment of skin lesions offers substantial additional diagnostic value for clinicians. THz images contain information complementary to the information contained in the conventional digital images.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2024 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Electronic & Electrical Engineering (Leeds) > Pollard Institute (Leeds) |
Funding Information: | Funder Grant number University of Queensland Sustainable Minerals Institute Not Known EPSRC (Engineering and Physical Sciences Research Council) EP/T034246/1 |
Depositing User: | Symplectic Publications |
Date Deposited: | 04 Mar 2024 11:55 |
Last Modified: | 12 Mar 2024 15:15 |
Status: | Published |
Publisher: | AIP Publishing |
Identification Number: | 10.1063/5.0190573 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:209819 |