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Munyombwe, T. orcid.org/0000-0002-1307-6691, Dondo, T.B., Hall, M. orcid.org/0000-0003-1246-2627 et al. (10 more authors) (2023) Cohort profile: Evaluation of the Methods and Management of Acute Coronary Events (EMMACE) longitudinal cohort. European Heart Journal - Quality of Care and Clinical Outcomes, 9 (5). pp. 442-446. ISSN 2058-5225
Abstract
Aims The Evaluation of the Methods and Management of Acute Coronary Events (EMMACE) longitudinal cohort study aims to investigate health trajectories of individuals following hospitalization for myocardial infarction (MI).
Methods and results EMMACE is a linked multicentre prospective cohort study of 14 899 patients with MI admitted to 77 hospitals in England who participated in the EMMACE-3 and -4 studies between 1st November 2011 and 24th June 2015. Long-term follow-up of the EMMACE cohorts was conducted through the EMMACE-XL (27th September 2020 to 31st March 2022) and EMMACE-XXL (1st July 2021 to 1st July 2023) studies. EMMACE collected individual participant data for health-related quality of life (HRQoL) measured by three-level EuroQol five-dimension and visual analogy scale at admission, 1 month, 6 months, 12 months, and 10 years follow-up, as well as medications, medication adherence, beliefs about medicines, Satisfaction with Information about Medicines Scale, and illness perceptions. Participant data were deterministically linked to the Myocardial Infarction National Audit Project (MINAP) for information on baseline treatments and comorbidities, Hospital Episode Statistics Admitted Patient Care (for cause-specific hospitalization data), and the Office for National Statistics (for mortality data) up to 2020.
Conclusion EMMACE is a nationwide prospective cohort that will provide unique insights into fatal and non-fatal outcomes, medication adherence, and HRQoL following MI.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology. This is an open access article under the terms of the Creative Commons Attribution License (CC-BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited. |
Keywords: | Myocardial infarction, Outcomes, Hospitalizations, Medications, Health-related quality of life, Cohort, Electronic health records, Longitudinal data |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Environment (Leeds) > School of Geography (Leeds) > Centre for Spatial Analysis & Policy (Leeds) The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM) > Clinical & Population Science Dept (Leeds) The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Health Sciences (Leeds) > Centre for Health Services Research (Leeds) The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Medical Research (LIMR) |
Funding Information: | Funder Grant number British Heart Foundation PG/19/54/34511 Wellcome Trust 206470/Z/17/Z |
Depositing User: | Symplectic Publications |
Date Deposited: | 01 Feb 2024 12:24 |
Last Modified: | 01 Feb 2024 12:24 |
Published Version: | http://dx.doi.org/10.1093/ehjqcco/qcad040 |
Status: | Published |
Publisher: | Oxford University Press |
Identification Number: | 10.1093/ehjqcco/qcad040 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:208555 |
Available Versions of this Item
- Cohort profile: Evaluation of the Methods and Management of Acute Coronary Events (EMMACE) longitudinal cohort. (deposited 01 Feb 2024 12:24) [Currently Displayed]