Sensale, M. orcid.org/0000-0003-3058-1259, Vendeuvre, T., Germaneau, A. et al. (3 more authors) (2023) Prediction of the 3D shape of the L1 vertebral body from adjacent vertebrae. Medical Image Analysis, 87. 102827. ISSN 1361-8415
Abstract
The aim of treatments of vertebral fractures is the anatomical reduction to restore the physiological biomechanics of the spine and the stabilization of the fracture to allow bone healing. However, the three-dimensional shape of the fractured vertebral body before the fracture is unknown in the clinical setting. Information about the pre-fracture vertebral body shape could help surgeons to select the optimal treatment. The goal of this study was to develop and validate a method based on Singular Value Decomposition (SVD) to predict the shape of the vertebral body of L1 from the shapes of T12 and L2. The geometry of the vertebral bodies of T12, L1 and L2 vertebrae of 40 patients were extracted from CT scans available from the VerSe2020 open-access dataset. Surface triangular meshes of each vertebra were morphed onto a template mesh. The set of vectors with the node coordinates of the morphed T12, L1 and L2 were compressed with SVD and used to build a system of linear equations. This system was used to solve a minimization problem and to reconstruct the shape of L1. A leave-one-out cross-validation was performed. Moreover, the approach was tested against an independent dataset with large osteophytes. The results of the study show a good prediction of the shape of the vertebral body of L1 from the shapes of the two adjacent vertebrae (mean error equal to 0.51 ± 0.11 mm on average, Hausdorff distance equal to 2.11 ± 0.56 mm on average), compared to current CT resolution typically used in the operating room. The error was slightly higher for patients presenting large osteophytes or severe bone degeneration (mean error equal to 0.65 ± 0.10 mm, Hausdorff distance equal to 3.54 ± 1.03 mm). The accuracy of the prediction was significantly better than approximating the shape of the vertebral body of L1 by the shape of T12 or L2. This approach could be used in the future to improve the pre-planning of spine surgeries to treat vertebral fractures.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2023 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
Keywords: | CT-scan images; Shape prediction; Statistical shape modeling; Vertebral fractures; Humans; Vertebral Body; Osteophyte; Thoracic Vertebrae; Spinal Fractures; Lumbar Vertebrae |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine and Population Health |
Funding Information: | Funder Grant number EUROPEAN COMMISSION - HORIZON 2020 766012 ENGINEERING AND PHYSICAL SCIENCE RESEARCH COUNCIL EP/S032940/1 Engineering and Physical Sciences Research Council EP/K03877X/1 |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 31 Jan 2024 14:31 |
Last Modified: | 31 Jan 2024 14:31 |
Status: | Published |
Publisher: | Elsevier BV |
Refereed: | Yes |
Identification Number: | 10.1016/j.media.2023.102827 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:208312 |