Northage, Naomi, Simon, Stéphane, Shvalya, Vasyl et al. (5 more authors) (2023) Efficient endoscope inner channel surface disinfection using a two-step atmospheric pressure plasma treatment. APPLIED SURFACE SCIENCE. 156936. ISSN 0169-4332
Abstract
Flexible endoscopes are ubiquitously used in modern medicine to diagnose and treat a variety of gastrointestinal ailments; however, the inner channels of these complex devices provide an ideal environment for biofilm development. Incomplete or ineffective endoscope reprocessing introduces the potential for cross-contamination between patients, highlighting the need for a new approach to disinfection. In this study, the antibiofilm potential of a two-step disinfection process using cold atmospheric pressure plasma and plasma activated water is considered. It was revealed that the combined approach achieved a 5.72 log reduction of clinically relevant mixed species biofilms from the narrow lumens found within a typical endoscope. To investigate potential surface damage resulting from the decontamination process, the surface composition and morphology were examined using XPS, FTIR and AFM. Following multiple disinfection cycles, few changes to the surface composition or morphology were detected and the corresponding ability of bacteria to adhere on the surface was not enhanced.
Metadata
Item Type: | Article |
---|---|
Authors/Creators: |
|
Copyright, Publisher and Additional Information: | Funding Information: The authors gratefully acknowledge financial support from the Engineering and Physical Sciences Research Council (Projects EP/N021347/1 and EP/S025790/1) and Public Agency for Research Activity of the Republic of Slovenia (ARRS) grants J2-4451 and J2-4490. The authors are thankful to Olympus Surgical Technologies Europe for provision of the endoscopic test materials and pH buffered peracetic acid. Publisher Copyright: © 2023 The Author(s) |
Keywords: | Cold atmospheric plasma,Endoscope reprocessing,Plasma activated water,Reactive oxygen and nitrogen species,Surface damage |
Dates: |
|
Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Physics (York) |
Depositing User: | Pure (York) |
Date Deposited: | 12 Jan 2024 11:00 |
Last Modified: | 16 Oct 2024 19:42 |
Published Version: | https://doi.org/10.1016/j.apsusc.2023.156936 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1016/j.apsusc.2023.156936 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:207524 |
Download
Filename: 1-s2.0-S0169433223006128-main.pdf
Description: Efficient endoscope inner channel surface disinfection using a two-step atmospheric pressure plasma treatment
Licence: CC-BY 2.5