Denis, Dan orcid.org/0000-0003-3740-7587 and Cairney, Scott Ashley orcid.org/0000-0002-1135-6059 (2023) Neural reactivation during human sleep. Emerging Topics in Life Sciences. ISSN 2397-8562
Abstract
Sleep promotes memory consolidation: the process by which newly acquired memories are stabilised, strengthened, and integrated into long-term storage. Pioneering research in rodents has revealed that memory reactivation in sleep is a primary mechanism underpinning sleep’s beneficial effect on memory. In this review, we consider evidence for memory reactivation processes occurring in human sleep. Converging lines of research support the view that memory reactivation occurs during human sleep, and is functionally relevant for consolidation. Electrophysiology studies have shown that memory reactivation is tightly coupled to the cardinal neural oscillations of non-rapid eye movement sleep, namely slow oscillation-spindle events. In addition, functional imaging studies have found that brain regions recruited during learning become reactivated during post-learning sleep. In sum, the current evidence paints a strong case for a mechanistic role of neural reactivation in promoting memory consolidation during human sleep.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2023 The Author(s) |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Psychology (York) |
Funding Information: | Funder Grant number EUROPEAN COMMISSION 101028886 MEDICAL RESEARCH COUNCIL (MRC) MR/P020208/1 |
Depositing User: | Pure (York) |
Date Deposited: | 13 Dec 2023 10:30 |
Last Modified: | 27 Feb 2025 00:08 |
Published Version: | https://doi.org/10.1042/ETLS20230109 |
Status: | Published online |
Refereed: | Yes |
Identification Number: | 10.1042/ETLS20230109 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:206595 |
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Description: Neural reactivation during human sleep
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