Collerton, Daniel, Barnes, James, Diederich, Nico J. et al. (18 more authors) (2023) Understanding visual hallucinations:A new synthesis. Neuroscience and Biobehavioral Reviews. 105208. ISSN 0149-7634
Abstract
Despite decades of research, we do not definitively know how people sometimes see things that are not there. Eight models of complex visual hallucinations have been published since 2000, including Deafferentation, Reality Monitoring, Perception and Attention Deficit, Activation, Input, and Modulation, Hodological, Attentional Networks, Active Inference, and Thalamocortical Dysrhythmia Default Mode Network Decoupling. Each was derived from different understandings of brain organisation. To reduce this variability, representatives from each research group agreed an integrated Visual Hallucination Framework that is consistent with current theories of veridical and hallucinatory vision. The Framework delineates cognitive systems relevant to hallucinations. It allows a systematic, consistent, investigation of relationships between the phenomenology of visual hallucinations and changes in underpinning cognitive structures. The episodic nature of hallucinations highlights separate factors associated with the onset, persistence, and end of specific hallucinations suggesting a complex relationship between state and trait markers of hallucination risk. In addition to a harmonised interpretation of existing evidence, the Framework highlights new avenues of research, and potentially, new approaches to treating distressing hallucinations.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | Funding Information: Robert Dudley receives grant income for trials of psychological therapy for unusual experiences like visions (NIHR), works in the NHS offering treatment for visual hallucinations, and receives workshop fees for teaching on this topic.Dominic H ffytche was supported by the National Institute for Health Research (NIHR) Maudsley Biomedical Research Centre and Dementia Unit and, with John-Paul Taylor and Daniel Collerton, NIHR Programme Grants for Applied Research (SHAPED RP-PG-0610–10100).Christopher C Goetz has received funding to Rush University Medical Center from National Institutes of Health, Department of Defense, Parkinson's Foundation. and Michael J. Fox Foundation for Research.Shigetoshi Nara was supported by JSPS KAKENHI Grant Numbers JP17H01794, JP20H04246, JP20K11985, JP20K12002, and the Cooperative Research Program of "Network Joint Research Center for Materials and Devices".Claire O'Callaghan was supported by a Neil Hamilton Fairley Fellowship from the Australian National Health and Medical Research Council (GNT1091310).Simon Lewis is supported by a National Health and Medical Research Council Leadership Fellowship (1195830).Ichiro Tsuda was partially supported by the JST Strategic Basic Research Programs (Symbiotic Interaction: Creation and Development of Core Technologies Interfacing Human and Information Environments, CREST Grant Number JPMJCR17A4). He was also partially supported by a Grant-in-Aid for Scientific Research on Innovative Areas (Non-Linear Neuro-Oscillology: Towards Integrative Understanding of Human Nature, KAKENHI Grant Number 15H05878), and Grant Number 17H01794 from the Ministry of Education, Culture, Sports, Science and Technology, Japan.Rimona S Weil receives a Wellcome Clinical Research Career Development Fellowship (205167/16/Z). Funding Information: Christopher C Goetz has received funding to Rush University Medical Center from National Institutes of Health , Department of Defense, Parkinson’s Foundation. and Michael J. Fox Foundation for Research. Funding Information: Marco Onofrj has served on the scientific advisory boards of GlaxoSmithKline, Novartis, Lundbeck, Eisai, Valeant, Medtronic, and Newron; has received speaker honoraria from Zambon, the World Parkinson Congress, the Movement Disorder Society, and the Atypical Dementias congress; publishing royalties from Springer; was an invited guest and lecturer for the Mental Disorders in Parkinson Disease Congress; serves on the editorial board of Medicine (Baltimore) and Frontiers in Neuroscience; has been employed as a speaker for Boehringer Ingelheim, GlaxoSmithKline, UCB, and Zambon; and has received research support from the Italian Ministry of Health and the Italian Ministry of Education. Funding Information: Ichiro Tsuda was partially supported by the JST Strategic Basic Research Programs (Symbiotic Interaction: Creation and Development of Core Technologies Interfacing Human and Information Environments, CREST Grant Number JPMJCR17A4). He was also partially supported by a Grant-in-Aid for Scientific Research on Innovative Areas (Non-Linear Neuro-Oscillology: Towards Integrative Understanding of Human Nature, KAKENHI Grant Number 15H05878 ), and Grant Number 17H01794 from the Ministry of Education, Culture, Sports, Science and Technology, Japan. Funding Information: Simon Lewis is supported by a National Health and Medical Research Council Leadership Fellowship ( 1195830 ). Funding Information: Claire O’Callaghan was supported by a Neil Hamilton Fairley Fellowship from the Australian National Health and Medical Research Council ( GNT1091310 ). Funding Information: James M Shine was supported by a project grant from the Australian National Health and Medical Research Council ( GNT1156536 ). Funding Information: Dominic H ffytche was supported by the National Institute for Health Research (NIHR) Maudsley Biomedical Research Centre and Dementia Unit and, with John-Paul Taylor and Daniel Collerton, NIHR Programme Grants for Applied Research ( SHAPED RP-PG-0610–10100 ). Funding Information: Glenn T Stebbins has received grant and research support from National Institutes of Health, Department of Defense, Michael J. Fox Foundation for Parkinson’s Research, Dystonia Coalition, CHDI Management, Cleveland Clinic Foundation, International Parkinson and Movement Disorder Society, CBD Solutions. Honoraria were received from the International Parkinson and Movement Disorder Society, American Academy of Neurology, Michael J. Fox Foundation for Parkinson’s Research, Food and Drug Administration, National Institutes of Health, Alzheimer's Association. Salary support was received from Rush University Medical Center. Funding Information: John-Paul Taylor is supported by the NIHR Newcastle Biomedical Research Centre. Funding Information: Jennifer G Goldman has received salary support from Shirley Ryan AbilityLab, Lewy Body Dementia Association Research Center of Excellence, Acadia, American Parkinson’s Disease Association, Michael J. Fox Foundation, and Parkinson’s Foundation; honoraria from International Parkinson and Movement Disorder Society, and Parkinson’s Foundation. Funding Information: Shigetoshi Nara was supported by JSPS KAKENHI Grant Numbers JP17H01794 , JP20H04246 , JP20K11985 , JP20K12002 , and the Cooperative Research Program of "Network Joint Research Center for Materials and Devices". Publisher Copyright: © 2023 The Authors |
Keywords: | Anomalous experiences,Charles Bonnet syndrome,Eye disease,Lewy body,Misperception,Psychosis,Vision,Visual hallucination,Visual perception |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Psychology (York) |
Depositing User: | Pure (York) |
Date Deposited: | 07 Dec 2023 11:40 |
Last Modified: | 11 Apr 2025 23:32 |
Published Version: | https://doi.org/10.1016/j.neubiorev.2023.105208 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1016/j.neubiorev.2023.105208 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:206327 |
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Description: Understanding visual hallucinations: A new synthesis
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