Elevated levels of MMP12 sourced from macrophages are associated with poor prognosis in urothelial bladder cancer

Kerzeli, I.K., Kostakis, A., Türker, P. et al. (8 more authors) (2023) Elevated levels of MMP12 sourced from macrophages are associated with poor prognosis in urothelial bladder cancer. BMC Cancer, 23 (1). 605. ISSN 1471-2407

Abstract

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Item Type: Article
Authors/Creators:
  • Kerzeli, I.K.
  • Kostakis, A.
  • Türker, P.
  • Malmström, P.-U.
  • Hemdan, T.
  • Mezheyeuski, A.
  • Ward, D.G.
  • Bryan, R.T.
  • Segersten, U.
  • Lord, M.
  • Mangsbo, S.M.
Copyright, Publisher and Additional Information:

© 2023 The Author(s). Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativeco mmons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

Keywords: Biomarkers; Macrophages; Matrix metalloproteinase 12 (MMP12); Proteomics; Proximity Extension Assay (PEA); Single-cell transcriptomics; Urothelial bladder cancer; Humans; Animals; Mice; Matrix Metalloproteinase 12; Proteomics; Quality of Life; Urinary Bladder Neoplasms; Carcinoma, Transitional Cell; Macrophages; Prognosis; Tumor Microenvironment
Dates:
  • Published: 30 June 2023
  • Published (online): 30 June 2023
  • Accepted: 21 June 2023
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Science (Sheffield) > Department of Psychology (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 01 Dec 2023 10:22
Last Modified: 01 Dec 2023 10:22
Status: Published
Publisher: Springer Science and Business Media LLC
Refereed: Yes
Identification Number: 10.1186/s12885-023-11100-0
Related URLs:
Open Archives Initiative ID (OAI ID):

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