Tangsombun, Chayanan and Smith, David K. orcid.org/0000-0002-9881-2714 (2023) Fabricating Shaped and Patterned Supramolecular Multi-Gelator Objects via Diffusion-Adhesion Gel Assembly. Journal of the American Chemical Society. jacs.3c07376. pp. 24061-24070. ISSN 1520-5126
Abstract
We report the use of acid-diffusion to assemble core-shell supramolecular gel beads with different low-molecular-weight gelators (LMWGs) in the core and shell. These gel beads grow a shell of dibenzylidenesorbitol-based DBS-COOH onto a core comprising DBS-CONHNH2 and agarose that has been loaded with acetic acid. Diffusion of the acid from the core triggers shell assembly. The presence of DBS-CONHNH2 enables the gel core to be loaded with metal nanoparticles (NPs) as the acyl hydrazide reduces metal salts in situ. The pH-responsiveness of DBS-COOH allows responsive assembly of the shell with both temporal and spatial control. By fixing multiple gel beads in a petri dish, the cores become linked to one another by the as-sembled DBS-COOH gel shell – a process we describe as diffusion-adhesion assembly. By controlling the geometry of the beads with respect to one another, it is possible to pattern the structures, and using a layer-by-layer approach, 3D objects can be fabricated. If some of the beads are loaded with basic DBS-carboxylate instead of CH3COOH, they act as a ‘sink’ for diffusing protons, preventing DBS-COOH shell assembly in the close proximity. Those beads do not adhere to the remainder of the growing gel object and can be simply removed once diffusion-assembly is complete, acting as templates, and enabling the fabrication of 3D ‘imprinted’ multi-gel architectures. Pre-loading the gel beads with AuNPs or AgNPs suspends these func-tional units within the cores at precisely-defined locations within a wider gel object. In summary, this approach enables the fabrication of shaped and patterned gels with embedded metal NPs – such objects have potential next-generation applica-tions in areas including soft nanoelectronics and regenerative medicine.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2023 The Authors. |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Chemistry (York) |
Depositing User: | Pure (York) |
Date Deposited: | 27 Oct 2023 14:30 |
Last Modified: | 27 Nov 2024 00:47 |
Published Version: | https://doi.org/10.1021/jacs.3c07376 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1021/jacs.3c07376 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:204665 |
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Description: tangsombun-smith-2023-fabricating-shaped-and-patterned-supramolecular-multigelator-objects-via-diffusion-adhesion-gel
Licence: CC-BY 2.5