Zhang, H., Li, W., Wang, Y. et al. (4 more authors) (2023) Foods, nutrients and risk of in-hospital frailty in women: findings from a large prospective cohort study. Nutrients, 15 (21). 4619. ISSN 2072-6643
Abstract
Frailty is increasingly prevalent worldwide because of aging populations. Diet may play a role as a modifiable risk factor. This study aimed to investigate associations between die-tary factors and risk of frailty in the UK Women’s Cohort admitted to hospitals in England. Consumption of foods and nutrients were estimated using a validated 217-item food frequency questionnaire at baseline. Incident frailty was assessed via a hospital frailty risk score based on linkage with hospital episode statistics. Out of 25,186 participants admitted to hospitals, 6919 (27%) were identified with frailty and 10,562 (42%) with pre-frailty over a mean follow-up of 12.7 years. After adjustment for confounding, we observed a 12% increase in risk of frailty with each additional 10g/MJ intake of total meat (HR=1.12, 95%CI: 1.07, 1.17), with the highest risk observed for processed meats (HR=1.45, 95%CI: 1.21, 1.73). Similar associations were observed with pre-frailty and more severe. Vegetable intake was associated with slightly lower risk of frailty (HR=0.98, 95%CI: 0.97, 1.00). There was no evidence of association between most nutrient intakes and in-hospital frailty risk. Overall, our findings suggest that reducing consumption of meat, especially processed meat, in adults may be beneficial regarding the development of frailty.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
Keywords: | Frailty; Dietary intakes; Meat consumption; Processed meat; Nutrients; Hospital Episode Statistics |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM) > Clinical & Population Science Dept (Leeds) |
Funding Information: | Funder Grant number World Cancer Research Fund EX 450562 |
Depositing User: | Symplectic Publications |
Date Deposited: | 24 Oct 2023 08:50 |
Last Modified: | 16 Nov 2023 17:03 |
Status: | Published |
Publisher: | MDPI |
Identification Number: | 10.3390/nu15214619 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:204486 |