Saunders, L.C. orcid.org/0000-0002-1080-9861, Hughes, P.J.C. orcid.org/0000-0002-7979-5840, Alabed, S. orcid.org/0000-0002-9960-7587 et al. (7 more authors) (2022) Integrated cardiopulmonary MRI assessment of pulmonary hypertension. Journal of Magnetic Resonance Imaging, 55 (3). pp. 633-652. ISSN 1053-1807
Abstract
Pulmonary hypertension (PH) is a heterogeneous condition that can affect the lung parenchyma, pulmonary vasculature, and cardiac chambers. Accurate diagnosis often requires multiple complex assessments of the cardiac and pulmonary systems. MRI is able to comprehensively assess cardiac structure and function, as well as lung parenchymal, pulmonary vascular, and functional lung changes. Therefore, MRI has the potential to provide an integrated functional and structural assessment of the cardiopulmonary system in a single exam. Cardiac MRI is used in the assessment of PH in most large PH centers, whereas lung MRI is an emerging technique in patients with PH. This article reviews the current literature on cardiopulmonary MRI in PH, including cine MRI, black-blood imaging, late gadolinium enhancement, T1 mapping, myocardial strain analysis, contrast-enhanced perfusion imaging and contrast-enhanced MR angiography, and hyperpolarized gas functional lung imaging. This article also highlights recent developments in this field and areas of interest for future research including cardiac MRI-based diagnostic models, machine learning in cardiac MRI, oxygen-enhanced 1H imaging, contrast-free 1H perfusion and ventilation imaging, contrast-free angiography and UTE imaging.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2021 The Authors. Journal of Magnetic Resonance Imaging published by Wiley Periodicals LLC on behalf of International Society for Magnetic Resonance in Medicine. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited (https://creativecommons.org/licenses/by/4.0/). |
Keywords: | cardiac; cardiopulmonary; lung; pulmonary; pulmonary hypertension; Contrast Media; Gadolinium; Humans; Hypertension, Pulmonary; Lung; Magnetic Resonance Imaging |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > The Medical School (Sheffield) The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine and Population Health |
Funding Information: | Funder Grant number MEDICAL RESEARCH COUNCIL MR/M008894/1 WELLCOME TRUST (THE) 205188/Z/16/Z |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 30 Aug 2023 15:33 |
Last Modified: | 30 Aug 2023 15:33 |
Status: | Published |
Publisher: | Wiley |
Refereed: | Yes |
Identification Number: | 10.1002/jmri.27849 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:202793 |
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