Targeted deletion of mek5 causes early embryonic death and defects in the extracellular signal-regulated kinase 5/myocyte enhancer factor 2 cell survival pathway

Wang, X., Merritt, A.J., Seyfried, J. et al. (9 more authors) (2005) Targeted deletion of mek5 causes early embryonic death and defects in the extracellular signal-regulated kinase 5/myocyte enhancer factor 2 cell survival pathway. Molecular and Cellular Biology, 25 (1). pp. 336-345. ISSN 0270-7306

Abstract

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Item Type: Article
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© 2005, American Society for Microbiology.

Keywords: Animals; Apoptosis; Blotting, Southern; Caspase 3; Caspases; Cell Death; Cell Proliferation; Cell Survival; Cells, Cultured; DNA-Binding Proteins; Enzyme Activation; Fibroblasts; Flow Cytometry; Gene Deletion; Genes, Reporter; Genetic Vectors; Genotype; Heterozygote; Immunoblotting; Immunohistochemistry; In Situ Nick-End Labeling; Luciferases; MAP Kinase Kinase 5; MEF2 Transcription Factors; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 7; Models, Genetic; Mutation; Myocardium; Myogenic Regulatory Factors; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Time Factors; Tissue Distribution; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transgenes
Dates:
  • Published: January 2005
  • Published (online): 27 March 2023
  • Accepted: 3 October 2004
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Science (Sheffield) > School of Biosciences (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 26 Jul 2023 10:20
Last Modified: 26 Jul 2023 10:26
Status: Published
Publisher: Informa UK Limited
Refereed: Yes
Identification Number: 10.1128/mcb.25.1.336-345.2005
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