Campbell, MK, Beard, DJ, Blazeby, JM et al. (2 more authors) (2023) Further considerations for placebo controls in surgical trials. Trials, 24. 391. ISSN 1745-6215
Abstract
The use of invasive placebo controls in surgical trials can be challenging. The ASPIRE guidance, published in the Lancet in 2020, provided advice for the design and conduct of surgical trials with an invasive placebo control. Based on a more recent international expert workshop in June 2022, we now provide further insights into this topic. These include the purpose and design of invasive placebo controls, patient information provision and how findings from these trials may be used to inform decision-making.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © The Author(s) 2023. This is an open access article under the terms of the Creative Commons Attribution License (CC-BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited. |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Inst of Clinical Trials Research (LICTR) (Leeds) |
Funding Information: | Funder Grant number NIHR National Inst Health Research NIHR302439 |
Depositing User: | Symplectic Publications |
Date Deposited: | 04 Jul 2023 09:46 |
Last Modified: | 04 Jul 2023 09:46 |
Status: | Published |
Publisher: | BMC |
Identification Number: | 10.1186/s13063-023-07417-7 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:201157 |