Independent endothelial functions of PIEZO1 and TRPV4 in hepatic portal vein and predominance of PIEZO1 in mechanical and osmotic stress

Endesh, N., Chuntharpursat-Bon, E., Revill, C. et al. (11 more authors) (2023) Independent endothelial functions of PIEZO1 and TRPV4 in hepatic portal vein and predominance of PIEZO1 in mechanical and osmotic stress. Liver International, 43 (9). pp. 2026-2038. ISSN 1478-3223

Abstract

Metadata

Item Type: Article
Authors/Creators:
  • Endesh, N.
  • Chuntharpursat-Bon, E.
  • Revill, C.
  • Yuldasheva, N. Y.
  • Futers, T. S.
  • Parsonage, G
  • Humphreys, N.
  • Adamson, A.
  • Morley, L. C.
  • Cubbon, R. M.
  • Prasad, K. R.
  • Foster, R.
  • Lichtenstein, L. ORCID logo https://orcid.org/0000-0003-3900-786X
  • Beech, D. J.
Copyright, Publisher and Additional Information:

© 2023 The Authors. Liver International published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Keywords: arachidonic; acid metabolism calcium signalling; calcium-permeable channel; endothelial nitric oxide synthase; endothelium; hepatobiliary system; liver; mechanical force; nitric oxide; non-selective cation channel; osmolality; PIEZO channel; portal vein; transient receptor potential; vanilloid 4 (TRPV4) channel; vascular relaxation; vasculature contraction; vein
Dates:
  • Published: September 2023
  • Published (online): 22 June 2023
  • Accepted: 31 May 2023
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM) > Discovery & Translational Science Dept (Leeds)
Funding Information:
Funder
Grant number
British Heart Foundation
RG/17/11/33042
Wellcome Trust
110044/Z/15/Z
Depositing User: Symplectic Publications
Date Deposited: 13 Jun 2023 15:26
Last Modified: 19 Nov 2024 15:53
Published Version: https://onlinelibrary.wiley.com/doi/10.1111/liv.15...
Status: Published
Publisher: Wiley
Identification Number: 10.1111/liv.15646
Open Archives Initiative ID (OAI ID):

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