Dialpuri, Jordan S, Bagdonas, Haroldas, Atanasova, Mihaela et al. (4 more authors) (2023) Analysis and validation of overall N-glycan conformation in Privateer. Acta crystallographica. Section D, Structural biology. 462–472. ISSN 2059-7983
Abstract
The oligosaccharides in N-glycosylation provide key structural and functional contributions to a glycoprotein. These contributions are dependent on the composition and overall conformation of the glycans. The Privateer software allows structural biologists to evaluate and improve the atomic structures of carbohydrates, including N-glycans; this software has recently been extended to check glycan composition through the use of glycomics data. Here, a broadening of the scope of the software to analyse and validate the overall conformation of N-glycans is presented, focusing on a newly compiled set of glycosidic linkage torsional preferences harvested from a curated set of glycoprotein models.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Chemistry (York) |
Depositing User: | Pure (York) |
Date Deposited: | 31 May 2023 09:40 |
Last Modified: | 16 Oct 2024 19:13 |
Published Version: | https://doi.org/10.1107/S2059798323003510 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1107/S2059798323003510 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:199777 |
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Description: Analysis and validation of overall N-glycan conformation in Privateer
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