(ADP-ribosyl)hydrolases: structural basis for differential substrate recognition and inhibition

Rack, J.G.M., Ariza, A. orcid.org/0000-0003-4364-823X, Drown, B.S. et al. (5 more authors) (2018) (ADP-ribosyl)hydrolases: structural basis for differential substrate recognition and inhibition. Cell Chemical Biology, 25 (12). E12. pp. 1533-1546. ISSN 2451-9456

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Item Type: Article
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© 2018 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Keywords: ADP-ribosylation; ADPRH; ADPRHL2; DNA damage; PARG; PARP; metalloenzyme; Adaptor Proteins, Signal Transducing; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycoside Hydrolases; Humans; Models, Molecular; Protein Conformation; Structure-Activity Relationship; Substrate Specificity
Dates:
  • Published: December 2018
  • Published (online): 21 November 2018
  • Accepted: 31 October 2018
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Science (Sheffield) > School of Biosciences (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 09 Jun 2023 14:25
Last Modified: 09 Jun 2023 14:25
Status: Published
Publisher: Elsevier BV
Refereed: Yes
Identification Number: 10.1016/j.chembiol.2018.11.001
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