A randomized, double-blind, biomarker-selected, phase II clinical trial of maintenance poly ADP-ribose polymerase inhibition with rucaparib following chemotherapy for metastatic urothelial carcinoma

Crabb, S.J. orcid.org/0000-0003-3521-9064, Hussain, S. orcid.org/0000-0003-1552-511X, Soulis, E. orcid.org/0000-0001-9022-9295 et al. (18 more authors) (2023) A randomized, double-blind, biomarker-selected, phase II clinical trial of maintenance poly ADP-ribose polymerase inhibition with rucaparib following chemotherapy for metastatic urothelial carcinoma. Journal of Clinical Oncology, 41 (1). pp. 54-64. ISSN 0732-183X

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Item Type: Article
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© 2022 by American Society of Clinical Oncology. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Keywords: Female; Humans; Ovarian Neoplasms; Poly(ADP-ribose) Polymerases; Carcinoma, Transitional Cell; Urinary Bladder Neoplasms; Platinum; Biomarkers; Adenosine Diphosphate Ribose; Double-Blind Method; Antineoplastic Combined Chemotherapy Protocols; Maintenance Chemotherapy
Dates:
  • Published: 1 January 2023
  • Published (online): 12 August 2022
  • Accepted: 20 June 2022
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > The Medical School (Sheffield) > Division of Genomic Medicine (Sheffield) > Department of Oncology and Metabolism (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 25 May 2023 08:51
Last Modified: 25 May 2023 08:51
Published Version: http://dx.doi.org/10.1200/jco.22.00405
Status: Published
Publisher: American Society of Clinical Oncology (ASCO)
Refereed: Yes
Identification Number: 10.1200/jco.22.00405
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