Minev, I.R. orcid.org/0000-0003-2055-7386 (2023) Electronic tissue technologies for seamless biointerfaces. Journal of Polymer Science, 61 (16). pp. 1707-1712. ISSN 2642-4150
Abstract
Bioelectronic interfaces establish a communication channel between a living system and an electrical machine. The first examples emerged in the 18th century when batteries were used to “galvanize” muscles and nerves. Today bioelectronic interfaces underpin key medical technologies such as the cardiac pacemaker and emerging ones such as neuroprostheses and brain-machine interfaces. Despite compelling applications in living systems, bioelectronic interfaces employ materials from microelectronics that are rigid, impermeable to water and bioinert. In contrast, electrical phenomena in soft tissues such as muscle and nerve are mediated by ions and molecules solvated in water. This disparity leads to missed opportunities for achieving seamless interfaces and communication that extends beyond electrical stimulation and recording. In this perspective, I discuss opportunities presented by hydrogel materials for building bioelectronic interfaces. This will require new types of hydrogels that support both ionic and electronic conductivity combined with key functions of the extracellular matrix.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2023 The Author. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. http://creativecommons.org/licenses/by-nc/4.0/ |
Keywords: | bioelectronics; conductive hydrogel; electrode arrays; neural interfaces |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Engineering (Sheffield) > Department of Automatic Control and Systems Engineering (Sheffield) |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 25 Apr 2023 14:29 |
Last Modified: | 02 Oct 2024 11:16 |
Status: | Published |
Publisher: | Wiley |
Refereed: | Yes |
Identification Number: | 10.1002/pol.20230111 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:198506 |