Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides

Bridges, Hannah R, Blaza, James N orcid.org/0000-0001-5420-2116, Yin, Zhan et al. (3 more authors) (2023) Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science (New York, N.Y.). pp. 351-357. ISSN 0036-8075

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Item Type: Article
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Keywords: Animals,Electron Transport Complex I/metabolism,Cryoelectron Microscopy,Metformin/pharmacology,Antimalarials/pharmacology,Mitochondria/metabolism,Mammals
Dates:
  • Published: 27 January 2023
  • Accepted: 23 December 2022
Institution: The University of York
Academic Units: The University of York > Faculty of Sciences (York) > Chemistry (York)
Depositing User: Pure (York)
Date Deposited: 22 Mar 2023 09:30
Last Modified: 07 Feb 2025 00:35
Published Version: https://doi.org/10.1126/science.ade3332
Status: Published
Refereed: Yes
Identification Number: 10.1126/science.ade3332
Open Archives Initiative ID (OAI ID):

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