Lockhart, P., Chu, V., Zhao, J. et al. (12 more authors) (2023) Oral hygiene and infective endocarditis: a case control study. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 136 (3). pp. 333-342. ISSN 2212-4403
Abstract
Objective
To determine if oral hygiene is associated with infective endocarditis (IE) among those at moderate risk for IE.
Study Design
This is a case control study of oral hygiene among hospitalized patients with IE (cases) and outpatients with heart valve disease but without IE (controls). The primary outcome was mean dental calculus index. Secondary outcomes included other measures of oral hygiene and periodontal disease (e.g., dental plaque, gingivitis) and categorization of blood culture bacterial species.
Results
The 62 case participants had 53% greater mean dental calculus index than the 119 control participants (0.84, 0.55, respectively; difference = 0.29, 95% CI:0.11, 0.48; p=0.002) and 26% greater mean dental plaque index (0.88, 0.70, respectively; difference = 0.18, 95% CI: 0.01,0.36; p=0.043). Overall, cases reported fewer dentist and dental hygiene visits (p= 0.013) and fewer dental visits in the 12 weeks prior to enrollment than controls (p=0.007). Common oral bacteria were identified from blood cultures in 27 of 62 cases (44%).
Conclusions
These data provide evidence to support and strengthen current AHA guidance that those at risk for IE can reduce potential sources of IE-related bacteremia by maintaining optimal oral health through regular professional dental care and oral hygiene procedures.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2023 Elsevier Inc. This is an author produced version of a paper subsequently published in Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. Uploaded in accordance with the publisher's self-archiving policy. Article available under the terms of the CC-BY-NC-ND licence (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
Keywords: | Infective endocarditis; Bacteremia; American Heart Association; Cardiac; Plaque; Calculus; Case Control; Oral hygiene |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Clinical Dentistry (Sheffield) |
Funding Information: | Funder Grant number NATIONAL INSTITUTES OF HEALTH - UNITED STATES OF AMERICA 1R01DE027917-01 NATIONAL INSTITUTES OF HEALTH - UNITED STATES OF AMERICA 1R01DE027917-01 NATIONAL INSTITUTES OF HEALTH - UNITED STATES OF AMERICA 1R01DE027917-01 NATIONAL INSTITUTES OF HEALTH - UNITED STATES OF AMERICA iR01DE023375-01A1 |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 06 Mar 2023 14:13 |
Last Modified: | 01 Oct 2024 07:59 |
Status: | Published |
Publisher: | Elsevier |
Refereed: | Yes |
Identification Number: | 10.1016/j.oooo.2023.02.020 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:196888 |
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Filename: IE Study Primary OOOOE FINAL VERSION Revised Feb 9 2023 (1).pdf
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