Laktionov, MY, Zhulina, EB, Klushin, L et al. (2 more authors) (2023) Selective colloid transport across planar polymer brushes. Macromolecular Rapid Communications, 44 (16). 2200980. ISSN 1022-1336
Abstract
Polymer brushes are attractive as surface coatings for a wide range of applications, from fundamental research to everyday life, and also play important roles in biological systems. How colloids (e.g., functional nanoparticles, proteins, viruses) bind and move across polymer brushes is an important yet under-studied problem. A mean-field theoretical approach is presented to analyze the binding and transport of colloids in planar polymer brushes. The theory explicitly considers the effect of solvent strength on brush conformation and of colloid-polymer affinity on colloid binding and transport. The position-dependent free energy of the colloid insertion into the polymer brush which controls the rate of colloid transport across the brush is derived. It is shown how the properties of the brush can be adjusted for brushes to be highly selective, effectively serving as tuneable gates with respect to colloid size and affinity to the brush-forming polymer. The most important parameter regime simultaneously allowing for high brush permeability and selectivity corresponds to a condition when the repulsive and attractive contributions to the colloid insertion free energy nearly cancel. This theory should be useful to design sensing and purification devices with enhanced selectivity and to better understand mechanisms underpinning the functions of biological polymer brushes.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2023 Wiley-VCH GmbH. This is the peer reviewed version of the following article: Laktionov, M. Y., Zhulina, E. B., Klushin, L., Richter, R. P., Borisov, O. V., Selective colloid transport across planar polymer brushes. Macromolecular Rapid Communications, 44 (16). 2200980, which has been published in final form at https://doi.org/10.1002/marc.202200980. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited. |
Keywords: | colloids; diffusion; macromolecular interactions; polymer brushes; selective transport |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Biomedical Sciences (Leeds) |
Funding Information: | Funder Grant number Royal Society IEC/R2/202035 BBSRC (Biotechnology & Biological Sciences Research Council) Not Known |
Depositing User: | Symplectic Publications |
Date Deposited: | 27 Feb 2023 16:55 |
Last Modified: | 13 Mar 2024 01:13 |
Status: | Published |
Publisher: | Wiley |
Identification Number: | 10.1002/marc.202200980 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:196784 |