Tasquinimod suppresses tumor cell growth and bone resorption by targeting immunosuppressive myeloid cells and inhibiting c-MYC expression in multiple myeloma

Fan, R. orcid.org/0000-0003-1032-4546, Satilmis, H., Vandewalle, N. et al. (16 more authors) (2023) Tasquinimod suppresses tumor cell growth and bone resorption by targeting immunosuppressive myeloid cells and inhibiting c-MYC expression in multiple myeloma. Journal for ImmunoTherapy of Cancer, 11 (1). e005319. ISSN 2051-1426

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Item Type: Article
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© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/ This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

Keywords: Hematologic Neoplasms; Immunomodulation; Immunotherapy; Myeloid-Derived Suppressor Cells; Animals; Mice; Bone Resorption; Cell Proliferation; Immunosuppressive Agents; Multiple Myeloma; Myeloid Cells; Quinolones; Tumor Microenvironment; Humans
Dates:
  • Published: January 2023
  • Published (online): 17 January 2023
  • Accepted: 30 December 2022
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > The Medical School (Sheffield) > Division of Genomic Medicine (Sheffield) > Department of Oncology and Metabolism (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 22 Feb 2023 10:49
Last Modified: 22 Feb 2023 10:49
Status: Published
Publisher: BMJ
Refereed: Yes
Identification Number: 10.1136/jitc-2022-005319
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Open Archives Initiative ID (OAI ID):

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