Loss of TMEM106B exacerbates C9ALS/FTD DPR pathology by disrupting autophagosome maturation

Bauer, C.S., Webster, C.P., Shaw, A.C. et al. (12 more authors) (2022) Loss of TMEM106B exacerbates C9ALS/FTD DPR pathology by disrupting autophagosome maturation. Frontiers in Cellular Neuroscience, 16. 1061559. ISSN 1662-5102

Abstract

Metadata

Item Type: Article
Authors/Creators:
  • Bauer, C.S.
  • Webster, C.P.
  • Shaw, A.C.
  • Kok, J.R.
  • Castelli, L.M.
  • Lin, Y.-H.
  • Smith, E.F.
  • Illanes-Álvarez, F.
  • Higginbottom, A.
  • Shaw, P.J.
  • Azzouz, M.
  • Ferraiuolo, L.
  • Hautbergue, G.M.
  • Grierson, A.J.
  • De Vos, K.J. ORCID logo https://orcid.org/0000-0003-2161-6309
Copyright, Publisher and Additional Information:

© 2022 Bauer, Webster, Shaw, Kok, Castelli, Lin, Smith, Illanes-Álvarez, Higginbottom, Shaw, Azzouz, Ferraiuolo, Hautbergue, Grierson and De Vos. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms (https://creativecommons.org/licenses/by/4.0/)

Keywords: C9orf72; DPR; autophagy; ALS/FTD; TMEM106B
Dates:
  • Published: 16 December 2022
  • Published (online): 16 December 2022
  • Accepted: 22 November 2022
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Sheffield Teaching Hospitals
The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Department of Neuroscience (Sheffield)
Funding Information:
Funder
Grant number
MOTOR NEURONE DISEASE ASSOCIATION
DeVos/Apr18/862-791
ALZHEIMER'S SOCIETY
260 (AS-PG-15-023)
Motor Neurone Disease Association
DeVos/Oct13/870-792
MEDICAL RESEARCH COUNCIL
MR/M013251/1
MEDICAL RESEARCH COUNCIL
MR/S025979/1
Motor Neurone Disease Association
MNDA-DeVos/Apr18/862-791
Motor Neurone Disease Association
MNDA-DeVos/Oct13/870-792
Depositing User: Symplectic Sheffield
Date Deposited: 20 Dec 2022 10:46
Last Modified: 20 Dec 2022 10:46
Status: Published
Publisher: Frontiers Media SA
Refereed: Yes
Identification Number: 10.3389/fncel.2022.1061559
Open Archives Initiative ID (OAI ID):

Export

Statistics