Bhattacharyya, S, Kochhar, KP and Jain, S (2022) Recording of motor and somatosensory evoked potential in an anaesthetised Wistar rat using digital polyrite system. Indian Journal of Physiology and Pharmacology, 66 (2). pp. 98-102. ISSN 0019-5499
Abstract
OBJECTIVES:
The aim of this article is to explain the detailed methodology to record Motor evoked potential (MEP) and somatosensory evoked potential (SSEP) in adult albino Wistar rat, male (200–250 g) which has not been defined previously.
MATERIALS AND METHODS:
We have standardised recording of both MEP and SSEP in these rats under anaesthesia on ADI digital polyrite system.
RESULTS:
Evoked potentials have been widely studied in spinal cord injured patients to estimate the degree of injury and to establish a predictive measure of functional recovery. MEPs and SSEPs, arising from the motor cortex or peripheral nerve and generated either by direct electrical stimulation or by transcranial magnetic stimulation, have been advocated as a reliable indicator of descending and ascending pathway integrity. In the rat brain, there is a physical overlap between the motor and somatosensory cortex. Hence, our objective was to identify the exact area for stimulation in the cortex where we could record maximum response with the application of minimum electrical stimulation.
CONCLUSION:
The recording of MEP and SSEP together provides a powerful neurological technique to monitor the tracts of the spinal cord.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2022 Published by Scientific Scholar on behalf of Indian Journal of Physiology and Pharmacology. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, transform, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
Keywords: | Corticospinal tracts, Motor evoked potential, Sensory-motor cortex, Somatosensory evoked potential, Wistar rats |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Biomedical Sciences (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 09 Dec 2022 15:02 |
Last Modified: | 09 Dec 2022 15:02 |
Status: | Published |
Publisher: | Scientific Scholar |
Identification Number: | 10.25259/ijpp_78_2022 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:193855 |