Mills, Greg B, Ratcovich, Hanna, Adams-Hall, Jennifer et al. (6 more authors) (2022) Is the contemporary care of the older persons with acute coronary syndrome evidence-based? European heart journal open. oeab044. ISSN 2752-4191
Abstract
Globally, ischaemic heart disease is the leading cause of death, with a higher mortality burden amongst older adults. Although advancing age is associated with a higher risk of adverse outcomes following acute coronary syndrome (ACS), older patients are less likely to receive evidence-based medications and coronary angiography. Guideline recommendations for managing ACS are often based on studies that exclude older patients, and more contemporary trials have been underpowered and produced inconsistent findings. There is also limited evidence for how frailty and comorbidity should influence management decisions. This review focuses on the current evidence base for the medical and percutaneous management of ACS in older patients and highlights the distinct need to enrol older patients with ACS into well-powered, large-scale randomized trials.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © The Author(s) 2021 |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Hull York Medical School (York) |
Depositing User: | Pure (York) |
Date Deposited: | 09 Nov 2022 12:00 |
Last Modified: | 21 Jan 2025 18:06 |
Published Version: | https://doi.org/10.1093/ehjopen/oeab044 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1093/ehjopen/oeab044 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:193161 |
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Description: Is the contemporary care of the older persons with acute coronary syndrome evidence-based?
Licence: CC-BY-NC 2.5