Mutually exclusive genetic interactions and gene essentiality shape the genomic landscape of primary melanoma.

Birkeälv, S, Harland, M, Matsuyama, LSAS et al. (15 more authors) (2023) Mutually exclusive genetic interactions and gene essentiality shape the genomic landscape of primary melanoma. Journal of Pathology, 259 (1). pp. 56-68. ISSN 0022-3417

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Item Type: Article
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© 2022 The Authors. The Journal of Pathology published by John Wiley & Sons Ltd on behalf of The Pathological Society of Great Britain and Ireland. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Keywords: Melanoma; gene essentiality; genetic epistasis; genomic landscape; CRISPR screening; IRF4; genome sequencing; somatic mutation; driver genes; primary cancer
Dates:
  • Published: January 2023
  • Published (online): 11 October 2022
  • Accepted: 28 September 2022
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Institute of Rheumatology & Musculoskeletal Medicine (LIRMM) (Leeds) > Experimental Musculoskeletal Medicine (Leeds)
Funding Information:
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Grant number
Cancer Research UK Supplier No: 138573
c588/A19167
Depositing User: Symplectic Publications
Date Deposited: 02 Nov 2022 16:20
Last Modified: 09 Jan 2023 15:01
Status: Published
Publisher: Wiley
Identification Number: 10.1002/path.6019
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