Durojaiye, O.C., Jibril, I. and Kritsotakis, E.I. orcid.org/0000-0002-9526-3852 (2022) Palliative outpatient parenteral antimicrobial therapy (OPAT): a single center experience and systematic scoping review. Clinical Infection in Practice, 16. 100205. ISSN 2590-1702
Abstract
Traditionally, outpatient parenteral antimicrobial therapy (OPAT) is used to treat infections with predictable course and anticipated response to therapy. However, there has been little consideration of OPAT for palliation as opposed to cure. This study presents a scoping review of literature and the experience of palliative OPAT at a tertiary referral hospital in Derbyshire, UK. Over the 5.5-year study period, six patients received OPAT for palliation (mean age 61 years). They accounted for 0.6 % (6/1044) and 3.1 % (1135/36658) of the total numbers of OPAT patients and bed-days saved, respectively. The literature search yielded 2375 articles, of which 5 case studies were eligible for review. Palliative OPAT provided positive experiences and outcomes for patients and their families. However, delivering palliative OPAT could be complex, time-consuming, and associated with clinical complications. There is a need for more research to address significant gaps in knowledge, especially regarding patient experiences and perspectives.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2022 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
Keywords: | Antimicrobial stewardship; Lifelong antimicrobial therapy; Outpatient parenteral antimicrobial therapy; Palliative care; Palliative OPAT |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Health and Related Research (Sheffield) > ScHARR - Sheffield Centre for Health and Related Research |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 13 Oct 2022 15:33 |
Last Modified: | 13 Oct 2022 15:33 |
Status: | Published |
Publisher: | Elsevier BV |
Refereed: | Yes |
Identification Number: | 10.1016/j.clinpr.2022.100205 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:191879 |