Valsamis, Epaminondas, Beard, David, Carr, Andrew et al. (7 more authors) (2022) Mapping the Oxford Shoulder Score onto the EQ‑5D utility index. Quality of life research. ISSN 1573-2649
Abstract
Abstract Purpose In order to enable cost-utility analysis of shoulder pain conditions and treatments, this study aimed to develop and evaluate mapping algorithms to estimate the EQ-5D health index from the Oxford Shoulder Score (OSS) when health outcomes are only assessed with the OSS. Methods 5437 paired OSS and EQ-5D questionnaire responses from four national multicentre randomised controlled trials investigating diferent shoulder pathologies and treatments were split into training and testing samples. Separate EQ-5D-3L and EQ-5D-5L analyses were undertaken. Transfer to utility (TTU) regression (univariate linear, polynomial, spline, multivariable linear, two-part logistic-linear, tobit and adjusted limited dependent variable mixture models) and response mapping (ordered logistic regression and seemingly unrelated regression (SUR)) models were developed on the training sample. These were internally validated, and their performance evaluated on the testing sample. Model performance was evaluated over 100-fold repeated training–testing sample splits. Results For the EQ-5D-3L analysis, the multivariable linear and splines models had the lowest mean square error (MSE) of 0.0415. The SUR model had the lowest mean absolute error (MAE) of 0.136. Model performance was greatest in the midrange and best health states, and lowest in poor health states. For the EQ-5D-5L analyses, the multivariable linear and splines models had the lowest MSE (0.0241–0.0278) while the SUR models had the lowest MAE (0.105–0.113). Conclusion The developed models now allow accurate estimation of the EQ-5D health index when only the OSS responses are available as a measure of patient-reported health outcome.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © The Author(s) 2022 |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Social Sciences (York) > Centre for Health Economics (York) The University of York > Faculty of Sciences (York) > Health Sciences (York) |
Depositing User: | Pure (York) |
Date Deposited: | 30 Sep 2022 08:40 |
Last Modified: | 23 Oct 2024 00:17 |
Published Version: | https://doi.org/10.1007/s11136-022-03262-4 |
Status: | Published online |
Refereed: | Yes |
Identification Number: | 10.1007/s11136-022-03262-4 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:191528 |
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Filename: s11136_022_03262_4.pdf
Description: Mapping the Oxford Shoulder Score onto the EQ‑5D utility index
Licence: CC-BY 2.5