Maksoud, F.J., de la Paz, F.V., Hann, A. et al. (5 more authors) (2022) Porous biomaterials for tissue engineering: a review. Journal of Materials Chemistry B, 40. pp. 8111-8165. ISSN 2050-750X
Abstract
The field of biomaterials has grown rapidly over the past decades. Within this field, porous biomaterials have played a remarkable role in: (i) enabling the manuface of complex three-dimensional structures; (ii) facilitating interconnected structures for the transport of macromolecules and cells; (iii) recreating mechanical properties close to those of the host tissues; and (iv) behaving as biocompatible inserts, tailored to either interact or not with the host body. This review outlines a brief history of the development of biomaterials, before discussing current materials proposed for use as porous biomaterials, and exploring the state-of-the-art in their manufacture. The wide clinical applications of these materials are extensively discussed, drawing on specific examples of how the porous features of such biomaterials impact their behaviours, as well as the advantages and challenges faced for each class of materials.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2022 Royal Society of Chemistry. This is an author-produced version of a paper subsequently published in Journal of Materials Chemistry B: Materials for biology and medicine. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | Polymers; Hydrogels; Fabrication Strategies; Bone Scaffolds; Auricular Tissue Grafts; Articular Cartilage Reconstruction; Vascular Regeneration; Pharmaceutical and Therapeutic Applications |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Engineering (Sheffield) > Department of Materials Science and Engineering (Sheffield) |
Funding Information: | Funder Grant number ROYAL SOCIETY IES\R3\183215 |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 22 Aug 2022 11:37 |
Last Modified: | 26 Jul 2023 00:13 |
Status: | Published |
Publisher: | Royal Society of Chemistry (RSC) |
Refereed: | Yes |
Identification Number: | 10.1039/d1tb02628c |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:190269 |