Da Silva, A.C. orcid.org/0000-0002-6258-9506, Paschoal, V.H., Ribeiro, M.C.C. et al. (1 more author) (2022) Electrical/spectroscopic stability of conducting and biodegradable graft‐copolymer. Macromolecular Chemistry and Physics, 223 (19). 2200275. ISSN 1022-1352
Abstract
Development of conductive and biodegradable graft-copolymers is decisive for applied electrical biointerfaces. However, to make significant breakthrough in bioelectronics, addressing changing properties while degrading is essential. Herein, the conductive and biodegradable poly(3,4-ethylenedioxythiophene) and poly(D,L-lactic acid) copolymer (PEDOT-co-PDLLA) submitted to 35 days of degradation in either deionized water or phosphate-buffered saline (PBS) is reported. Cyclic voltammetry, electrochemical impedance spectroscopy, and Raman microspectroscopy are used to correlate the electrical stability with molecular/structural changes during the degradation process. Two different proportions 1:05 (higher PEDOT content) and 1:50 (lower PEDOT content) are evaluated. The PEDOT-co-PDLLA 1:05 presents stable charge storage capacitance (CSC) in PBS for 35 days. PEDOT-co-PDLLA 1:50 shows an enhanced CSC when freshly prepared. However, it promptly loses its capacitance. Raman spectroscopy demonstrates that 1:05 as-prepared shows mostly neutral state. Nonetheless, after 35 days of degradation, both graft-copolymers show similar spectra, with contributions of oxidized states. Although the increase in oxidized states moieties should improve the conductivity, its dependence on interconnectivity and its relevance to remaining electronically stable, intrinsically related to conductive/biodegradable proportions in as-prepared graft-copolymer are demonstrated. This work contributes to a better understanding of the electrical stability of graft-copolymers for designing smart devices in bioelectronics applications.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2022 The Authors. Macromolecular Chemistry and Physics published by Wiley-VCH GmbH. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited (http://creativecommons.org/licenses/by/4.0/). |
Keywords: | biodegradable polymers; biomaterials; conducting polymers; graft-copolymers |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Engineering (Sheffield) > Department of Automatic Control and Systems Engineering (Sheffield) |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 25 Aug 2022 08:31 |
Last Modified: | 09 Jan 2023 11:44 |
Status: | Published |
Publisher: | Wiley |
Refereed: | Yes |
Identification Number: | 10.1002/macp.202200275 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:190247 |