Breitling, Rainer, Avbelj, Martina, Bilyk, Oksana et al. (19 more authors) (2021) Synthetic biology approaches to actinomycete strain improvement. FEMS microbiology letters. fnab060. ISSN 0378-1097
Abstract
Their biochemical versatility and biotechnological importance make actinomycete bacteria attractive targets for ambitious genetic engineering using the toolkit of synthetic biology. But their complex biology also poses unique challenges. This mini review discusses some of the recent advances in synthetic biology approaches from an actinomycete perspective and presents examples of their application to the rational improvement of industrially relevant strains.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | Funding Information: This review was funded through the European Union s Horizon 2020 Research and Innovation Programme under grant agreement number 720793 TOPCAPI Publisher Copyright: © 2021 The Author(s) 2021. Published by Oxford University Press on behalf of FEMS. |
Keywords: | Actinobacteria,Actinomycete,Biosynthesis,Biotechnology,Synthetic biology |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Centre for Immunology and Infection (CII) (York) The University of York > Faculty of Sciences (York) > Biology (York) |
Funding Information: | Funder Grant number EUROPEAN COMMISSION 720793 |
Depositing User: | Pure (York) |
Date Deposited: | 06 Jul 2022 10:50 |
Last Modified: | 25 Nov 2024 00:39 |
Published Version: | https://doi.org/10.1093/femsle/fnab060 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1093/femsle/fnab060 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:188784 |
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Description: Synthetic biology approaches to actinomycete strain improvement
Licence: CC-BY 2.5