Conaghan, PG orcid.org/0000-0002-3478-5665, Abraham, L, Viktrup, L et al. (5 more authors) (2022) The impact of osteoarthritis disease severity on treatment patterns and healthcare resource use: analysis of real-world data. Scandinavian Journal of Rheumatology. ISSN 0300-9742
Abstract
Objective
To understand treatment patterns and healthcare resource utilization (HCRU) related to osteoarthritis (OA) disease severity in patients in five European countries.
Method
Data were drawn from the Adelphi OA Disease Specific Programme™ (2017–18). Physicians classified their patients as having mild, moderate, or severe OA, and provided details on their current prescribed therapy and HCRU, including healthcare professional (HCP) consultations, diagnostics and testing, and hospitalizations. Comparisons between disease severity groups were made using analysis of variance and chi-squared tests.
Results
The study included 489 physicians (primary care physicians, rheumatologists, orthopaedic surgeons) reporting on 3596 OA patients: 24% mild, 53% moderate, and 23% severe disease. Both physicians and patients reported decreasing satisfaction with treatment with greater disease severity, despite the number of classes of prescribed drugs and increased use of opioids, which were used in almost half of patients with severe OA. For patients whose treatment was not effective, physicians prescribed the same therapeutic options, which were cycled in subsequent treatment lines, with multiple treatment regimens being commonly used. Patients with greater symptom severity also had more physician consultations, while the numbers of tests/imaging, predominantly X-rays, conducted to diagnose or monitor OA increased significantly with disease severity. The type of HCP involvement in patient management also varied by OA severity.
Conclusions
Across five European countries, the use of both non-pharmacological and pharmacological treatments increases with greater disease severity. Those with more severe disease place a greater demand on healthcare resources, with HCP consultations, tests, and hospital visits increasing with severity.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2022 Scandinavian Journal of Rheumatology Foundation. This is an author produced version of an article published in Scandinavian Journal of Rheumatology. Uploaded in accordance with the publisher's self-archiving policy. |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Institute of Rheumatology & Musculoskeletal Medicine (LIRMM) (Leeds) > Musculoskeletal Medicine & Imaging (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 12 May 2022 14:02 |
Last Modified: | 19 May 2023 00:13 |
Status: | Published online |
Publisher: | Taylor & Francis |
Identification Number: | 10.1080/03009742.2022.2058168 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:186654 |