Yildizbakan, L, Iqbal, N orcid.org/0000-0002-2801-707X, Abdulaziz, D et al. (5 more authors) (2022) Fabrication and Characterisation of Two-Layered Synthetic Titanium-Chitosan Bone Scaffolds. In: TMS 2022 151st Annual Meeting & Exhibition Supplemental Proceedings. TMS 2022 151st Annual Meeting & Exhibition, 27 Feb - 03 Mar 2022, Anaheim, California, USA. Springer, Cham , pp. 768-775. ISBN 9783030923808
Abstract
We have developed two-layered osteoconductive and antibacterial scaffolds, which mimic the natural structure of bone. The synthetic cortical (Type-1) biomaterials were fabricated from porous titanium embedded with 10% iron-doped brushite minerals. The trabecular (Type-2) biomaterials were fabricated from freeze-dried porous chitosan embedded with 10% iron-doped brushite and cerium oxide solution. The Type-1 and Type-2 biomaterials were conjoined during a freeze-drying process in a chamber maintained at −100 ℃ and 40 mTorr pressure; this approach aided the integration of the trabecular and cortical biomaterials, thus forming dual-layered scaffold. The two-layered scaffolds were characterised using Raman, and Fourier Transform Infrared (FTIR) Spectroscopy, Energy-Dispersive X-ray (EDX) Spectroscopy and Scanning Electron Microscopy (SEM) for their physicochemical and structural.
Metadata
Item Type: | Proceedings Paper |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2022 The Minerals, Metals & Materials Society. This is an author produced version of a conference paper published in TMS 2022 151st Annual Meeting & Exhibition Supplemental Proceedings. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | Biomaterials; Characterisation; Titanium; Bone scaffold |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Chemical & Process Engineering (Leeds) The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Institute of Rheumatology & Musculoskeletal Medicine (LIRMM) (Leeds) > Experimental Musculoskeletal Medicine (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 10 May 2022 09:39 |
Last Modified: | 07 Feb 2023 01:13 |
Status: | Published |
Publisher: | Springer, Cham |
Identification Number: | 10.1007/978-3-030-92381-5_73 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:186601 |