Guttesen, Anna, Gaskell, Gareth orcid.org/0000-0001-8325-1427, Madden, Emily et al. (3 more authors) (2023) Sleep loss disrupts the neural signature of successful learning. Cerebral Cortex. 1610–1625. ISSN 1460-2199
Abstract
Sleep supports memory consolidation as well as next-day learning. The influential Active Systems account of offline consolidation suggests that sleep-associated memory processing paves the way for new learning, but empirical evidence in support of this idea is scarce. Using a within-subjects (N = 30), crossover design, we assessed behavioural and electrophysiological indices of episodic encoding after a night of sleep or total sleep deprivation in healthy adults (aged 18-25 years), and investigated whether behavioural performance was predicted by the overnight consolidation of episodic associations formed the previous day. Sleep supported memory consolidation and next-day learning, as compared to sleep deprivation. However, the magnitude of this sleep-associated consolidation benefit did not significantly predict the ability to form novel memories after sleep. Interestingly, sleep deprivation prompted a qualitative change in the neural signature of encoding: whereas 12-20 Hz beta desynchronization – an established marker of successful encoding – was observed after sleep, sleep deprivation disrupted beta desynchrony during successful learning. Taken together, these findings suggest that effective learning depends on sleep, but not necessarily sleep-associated consolidation.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Psychology (York) |
Funding Information: | Funder Grant number MEDICAL RESEARCH COUNCIL (MRC) MR/P020208/1 |
Depositing User: | Pure (York) |
Date Deposited: | 04 Apr 2022 16:20 |
Last Modified: | 11 Jan 2025 00:08 |
Published Version: | https://doi.org/10.1093/cercor/bhac159 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1093/cercor/bhac159 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:185409 |
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