Parallel Optimisation of Potency and Pharmacokinetics Leading to the Discovery of a Pyrrole Carboxamide ERK5 Chemical Tool

Miller, Duncan C., Reuillon, Tristan, Molyneux, Lauren et al. (23 more authors) (2022) Parallel Optimisation of Potency and Pharmacokinetics Leading to the Discovery of a Pyrrole Carboxamide ERK5 Chemical Tool. JOURNAL OF MEDICINAL CHEMISTRY. pp. 6513-6540. ISSN: 0022-2623

Metadata

Item Type: Article
Authors/Creators:
  • Miller, Duncan C.
  • Reuillon, Tristan
  • Molyneux, Lauren
  • Blackburn, Timothy J.
  • Cook, Simon
  • Edwards, Noel
  • Endicott, Jane A.
  • Golding, Bernard T.
  • Griffin, Roger J.
  • Hardcastle, Ian R.
  • Heptinstall, Amy B.
  • Lochhead, Pamela
  • Martin, Mathew P.
  • Martin, Nick
  • Myers, Stephanie M.
  • Newell, David R.
  • Noble, Richard
  • Rigoreau, Laurent J.M.
  • Thomas, Huw
  • Tucker, Julie Ann ORCID logo https://orcid.org/0000-0002-6119-676X
  • Wang, Lan-Zhen
  • Waring, Michael J.
  • Wong, Ai-Ching
  • Wedge, Stephen
  • Noble, Martin
  • Cano, Celine
Copyright, Publisher and Additional Information:

© 2022 The Authors. Published by American Chemical Society
Dates:
  • Submitted: 11 October 2021
  • Accepted: 29 March 2022
  • Published (online): 25 April 2022
Institution: The University of York
Academic Units: The University of York > Faculty of Sciences (York) > Biology (York)
Depositing User: Pure (York)
Date Deposited: 01 Apr 2022 09:00
Last Modified: 17 Sep 2025 02:42
Published Version: https://doi.org/10.1021/acs.jmedchem.1c01756
Status: Published online
Refereed: Yes
Identification Number: 10.1021/acs.jmedchem.1c01756
Open Archives Initiative ID (OAI ID):

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