Increased SERCA2a sub-cellular heterogeneity in right-ventricular heart failure inhibits excitation-contraction coupling and modulates arrhythmogenic dynamics

Holmes, M, Hurley, ME orcid.org/0000-0003-0553-3079, Sheard, TMD orcid.org/0000-0003-4940-3188 et al. (3 more authors) (2022) Increased SERCA2a sub-cellular heterogeneity in right-ventricular heart failure inhibits excitation-contraction coupling and modulates arrhythmogenic dynamics. Philosophical Transactions of the Royal Society B: Biological Sciences, 377 (1864). 20210317. ISSN 0962-8436

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Item Type: Article
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© 2022 The Authors. Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.

Keywords: calcium handling, excitation-contraction coupling, arrhythmia, heterogeneity, serca, heart failure
Dates:
  • Published: 21 November 2022
  • Published (online): 3 October 2022
  • Accepted: 21 December 2021
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Biomedical Sciences (Leeds)
Funding Information:
Funder
Grant number
MRC (Medical Research Council)
MR/M014967/1
British Heart Foundation
PG/16/74/32374
Depositing User: Symplectic Publications
Date Deposited: 17 Jan 2022 10:50
Last Modified: 16 Oct 2022 17:44
Status: Published
Publisher: The Royal Society
Identification Number: 10.1098/rstb.2021.0317
Open Archives Initiative ID (OAI ID):

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