Proteinopathies as hallmarks of impaired gene expression, proteostasis and mitochondrial function in amyotrophic lateral sclerosis

Benson, B.C., Shaw, P.J. orcid.org/0000-0002-8925-2567, Azzouz, M. orcid.org/0000-0001-6564-5967 et al. (2 more authors) (2021) Proteinopathies as hallmarks of impaired gene expression, proteostasis and mitochondrial function in amyotrophic lateral sclerosis. Frontiers in Neuroscience, 15. 783624.

Abstract

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Item Type: Article
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© 2021 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

Keywords: proteinopathies; RNA metabolism alteration; mitochondrial dysfunction; impaired proteostasis; amyotrophic lateral sclerosis
Dates:
  • Published: 23 December 2021
  • Published (online): 23 December 2021
  • Accepted: 26 November 2021
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Sheffield Teaching Hospitals
Funding Information:
Funder
Grant number
Medical Research Council
MR/R024162/1
Biotechnology and Biological Sciences Research Council
BB/S005277/1
LifeArc
UNSPECIFIED
Depositing User: Symplectic Sheffield
Date Deposited: 13 Jan 2022 08:18
Last Modified: 13 Jan 2022 08:18
Status: Published
Publisher: Frontiers Media SA
Refereed: Yes
Identification Number: 10.3389/fnins.2021.783624
Open Archives Initiative ID (OAI ID):

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