Kanatas, A orcid.org/0000-0003-2025-748X, Lowe, D and Rogers, S (Cover date: April 2022) Health Related Quality of Life at 3 months following head and neck cancer treatment is a key predictor of longer-term outcome and of benefit from using the Patient Concerns Inventory. Cancer Medicine, 11 (8). pp. 1879-1890. ISSN 2045-7634
Abstract
Introduction
During clinical follow-up it can be difficult to identify those head and neck cancer (HNC) patients who are coping poorly and could benefit from additional support. Health-related quality of life (HRQOL) questionnaires and prompt lists provide a means by which patients can express their perceived outcomes and raise concerns. The first aim of this secondary analysis following a randomized trial was to explore which patient characteristics, at around 3 months following treatment completion (baseline), best predict HRQOL 12 months later. The second aim was to attempt to ascertain which patients were most likely to benefit from using prompt list.
Methods
Cluster-controlled pragmatic trial data were analyzed. HRQOL was measured by the University of Washington Quality of life questionnaire (UW-QOLv4). The prompt list was the Patient Concerns Inventory (PCI-HN).
Results
The trial involved 15 eligible consultants and a median (inter-quartile range) of 16 (13–26) primary HNC patients per consultant, with 140 PCI patients and 148 controls. Baseline HRQOL was the dominant predictor of 12-month HRQOL with other predictors related to social, financial, and lifestyle characteristics as well as clinical stage and treatment. Although formal statistical tests for interaction were non-significant the trend in analyses over a range of outcomes suggested that patients with worse baseline HRQOL could benefit more from the PCI-HN.
Discussion
HRQOL early post-treatment is a key predictor of longer-term outcome. Measuring and using HRQOL and the PCI-HN are not only surrogates for predicting HRQOL at 15 months post-treatment, but also tools to help guide interventions.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2022 The Authors. Cancer Medicine published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
Keywords: | health- related quality of life, patient concerns inventory, head and neck cancer |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Dentistry (Leeds) > School of Dentistry Visitors (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 12 Jan 2022 16:33 |
Last Modified: | 05 Sep 2023 14:48 |
Published Version: | https://onlinelibrary.wiley.com/doi/10.1002/cam4.4... |
Status: | Published |
Publisher: | Wiley |
Identification Number: | 10.1002/cam4.4558 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:181906 |